THERAPEUTIC EXERCISES AS THE MAIN MEANS OF PHYSICAL THERAPY IN CANCER PATIENTS WITH CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY (LITERATURE REVIEW)
DOI:
https://doi.org/10.32782/2221-1217-2025-1-02Keywords:
malignant neoplasm, physical therapy, peripheral neuropathy, chemotherapy, therapeutic exercisesAbstract
Oncological diseases are a problem of the healthcare system. In oncology, various treatment methods are used, chemotherapy is one of the most effective, but it leads to complications that worsen the quality of life of patients. Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of treatment that cannot be prevented or treated. CIPN manifests itself as sensory, motor and autonomic disorders and worsens the quality of life of cancer patients. In the literature, there are reports of the alleviation of CIPN symptoms when using physical therapy as a non-drug method of its correction or prevention. Most often, therapeutic exercises are used for the symptomatic treatment of CIPN, as well as manual therapy, massage, less often – electrotherapy and other means or methods of physical therapy. According to the analysis of the literature, it is most often recommended to use aerobic exercises, exercises for endurance or balance training, exercises for strength development, etc. Muscles in the process of muscle contraction secrete hormone-like substances myokines, the protective and regenerative role of which determines the positive effect of exercises in malignant neoplasms, however, their release is dosedependent, associated with the regimen, duration and intensity of physical exercises, which is confirmed by scientific studies. Most scientific works have found that exercises should not be prescribed in isolation and monotype, and the combination of various therapeutic exercises in physical therapy programs is more effective. Currently, there is still a need to create physical therapy programs that take into account specific symptoms of CIPN in cancer patients treated with various chemotherapy drugs and individual characteristics of patients to increase the effectiveness of rehabilitation interventions.
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